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RGLAX PHARMARglax Coat

AC-8

Moisture barrier for special category tablets

Solvent base barrier film for products outside the standard range.

Application

Moisture barrier film coat on a solvent base for special category tablets whose stability profile is not covered by the CVS, PA or MB grades. It is formulated against the specific core on request.

How it runs

Formulated against your specific core, so parameters are agreed at the trial rather than read off the standard table. Send the core and the stability problem you are trying to solve and we will work back from there.

Build-up and solids are fixed at trial.

The polymer

Polyvinyl alcohol (PVA)

PVA films are less permeable to water vapour than HPMC at the same thickness, which is what makes a moisture barrier a barrier. Our moisture barrier grades are fully formulated HPMC and PVA based immediate release systems, so the protection does not come at the cost of release.

Part of the Moisture Barrier Coating range.

Product code
AC-8
Coating system
Moisture Barrier Coating
Process base
Non-aqueous (solvent)
Finish
Moisture barrier
Supply form
Ready-mix, dispersed on site

How the coat sits on the tablet

Barrier filmHPMC and PVA based, low permeabilityTablet coreCompressed active and excipientsCross-section, not to scale
The barrier film is doing stability work, not cosmetic work. It slows water vapour reaching a core that would otherwise degrade in the pack.

Starting parameters

Rglax Coat film coating

Tablet bed and inlet temperatures are given as aqueous over non-aqueous (AQ / NAQ). Settings are indicative and confirmed against your core during trials.

Coating equipmentConventional coaterAQ / NAQ12 inch panAuto coaterAQ / NAQ24 inch panConventional coaterAQ / NAQ36 inch panAuto coaterAQ / NAQ48 inch pan
Pan speed (rpm)18 to 2014 to 168 to 123 to 5
Tablet charge (kg)0.5 to 13 to 540 to 50100 to 130
Tablet bed temp (°C)35-40 / 30-3535-40 / 30-3535-40 / 30-3535-40 / 30-35
Inlet temp (°C)75-80 / 60-6575-80 / 60-6575-80 / 60-6575-80 / 60-65

Common questions about AC-8

What if our core is not covered by CVS-101, PA-Wt10 or MB 31RP?

That is what AC-8 is for. It is a solvent base moisture barrier formulated against the specific core, so parameters are agreed at the trial rather than read off the standard table. Send the core and the stability problem you are trying to solve.