PA-Wt10
Extra white film coat for plain Amoxycillin
Solvent base extra white film for plain Amoxycillin and dissolution critical tablets.
Application
Solvent base extra white film coat for plain Amoxycillin tablets and other products where dissolution has to be protected while the core is covered to a high opacity.
Formulated for
- Amoxycillin
How it runs
Runs on the non-aqueous band. Dissolution rather than appearance is the constraint on these cores, so check dissolution at the end of the run and not only cover and gloss.
Build-up and solids are fixed at trial.
The polymer
Polyvinyl alcohol (PVA)
PVA films are less permeable to water vapour than HPMC at the same thickness, which is what makes a moisture barrier a barrier. Our moisture barrier grades are fully formulated HPMC and PVA based immediate release systems, so the protection does not come at the cost of release.
Part of the Moisture Barrier Coating range.
- Product code
- PA-Wt10
- Coating system
- Moisture Barrier Coating
- Process base
- Non-aqueous (solvent)
- Finish
- Extra white
- Supply form
- Ready-mix, dispersed on site
How the coat sits on the tablet
Starting parameters
Rglax Coat film coating
Tablet bed and inlet temperatures are given as aqueous over non-aqueous (AQ / NAQ). Settings are indicative and confirmed against your core during trials.
| Coating equipment | Conventional coaterAQ / NAQ12 inch pan | Auto coaterAQ / NAQ24 inch pan | Conventional coaterAQ / NAQ36 inch pan | Auto coaterAQ / NAQ48 inch pan |
|---|---|---|---|---|
| Pan speed (rpm) | 18 to 20 | 14 to 16 | 8 to 12 | 3 to 5 |
| Tablet charge (kg) | 0.5 to 1 | 3 to 5 | 40 to 50 | 100 to 130 |
| Tablet bed temp (°C) | 35-40 / 30-35 | 35-40 / 30-35 | 35-40 / 30-35 | 35-40 / 30-35 |
| Inlet temp (°C) | 75-80 / 60-65 | 75-80 / 60-65 | 75-80 / 60-65 | 75-80 / 60-65 |
Common questions about PA-Wt10
How does PA-Wt10 differ from CVS-101?
PA-Wt10 is for plain Amoxycillin and other dissolution critical tablets. CVS-101 is built for the Amoxycillin and Clavulanate combination, which carries a harder moisture problem.
What should be checked at the end of a run?
Dissolution, not only cover and gloss. On these cores dissolution is the constraint, so a batch that looks right can still fail the specification.