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RGLAX PHARMARglax Coat

MB 31RP

Moisture barrier for multivitamin and ferrous tablets

Solvent base barrier film for hygroscopic multivitamin and iron formulations.

Application

Solvent base moisture barrier film coat for Multivitamin and Ferrous group tablets. It protects the core from moisture pick-up and from the colour change that follows it on shelf.

Formulated for

  • Multivitamins
  • Ferrous group

How it runs

Multivitamin and ferrous cores are hygroscopic before they reach the coater, so the barrier film is carrying part of the shelf life. Watch colour on coated tablets through the first stability pulls, since colour drift is usually the first sign that the barrier is too thin.

Build-up and solids are fixed at trial.

The polymer

Polyvinyl alcohol (PVA)

PVA films are less permeable to water vapour than HPMC at the same thickness, which is what makes a moisture barrier a barrier. Our moisture barrier grades are fully formulated HPMC and PVA based immediate release systems, so the protection does not come at the cost of release.

Part of the Moisture Barrier Coating range.

Product code
MB 31RP
Coating system
Moisture Barrier Coating
Process base
Non-aqueous (solvent)
Finish
Colour or white, moisture barrier
Supply form
Ready-mix, dispersed on site

How the coat sits on the tablet

Barrier filmHPMC and PVA based, low permeabilityTablet coreCompressed active and excipientsCross-section, not to scale
The barrier film is doing stability work, not cosmetic work. It slows water vapour reaching a core that would otherwise degrade in the pack.

Starting parameters

Rglax Coat film coating

Tablet bed and inlet temperatures are given as aqueous over non-aqueous (AQ / NAQ). Settings are indicative and confirmed against your core during trials.

Coating equipmentConventional coaterAQ / NAQ12 inch panAuto coaterAQ / NAQ24 inch panConventional coaterAQ / NAQ36 inch panAuto coaterAQ / NAQ48 inch pan
Pan speed (rpm)18 to 2014 to 168 to 123 to 5
Tablet charge (kg)0.5 to 13 to 540 to 50100 to 130
Tablet bed temp (°C)35-40 / 30-3535-40 / 30-3535-40 / 30-3535-40 / 30-35
Inlet temp (°C)75-80 / 60-6575-80 / 60-6575-80 / 60-6575-80 / 60-65

Common questions about MB 31RP

Which products is MB 31RP used on?

Multivitamin and Ferrous group tablets. Both are hygroscopic before they reach the coater, so the barrier film carries part of the shelf life rather than only improving appearance.

What is the first sign the barrier is too thin?

Colour drift on coated tablets through the early stability pulls. Watch colour before you watch assay.